Divergent metabolic outcomes arising from targeted manipulation of the gut microbiota in diet-induced obesity Academic Article uri icon

Overview

MeSH Major

  • Anti-Bacterial Agents
  • Intestines
  • Obesity
  • Probiotics
  • Vancomycin

abstract

  • Both vancomycin and the bacteriocin-producing probiotic altered the gut microbiota in diet-induced obese mice, but in distinct ways. Only vancomycin treatment resulted in an improvement in the metabolic abnormalities associated with obesity thereby establishing that while the gut microbiota is a realistic therapeutic target, the specificity of the antimicrobial agent employed is critical.

publication date

  • February 2013

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1136/gutjnl-2011-300705

PubMed ID

  • 22345653

Additional Document Info

start page

  • 220

end page

  • 6

volume

  • 62

number

  • 2