Association of KRAS and EGFR mutations with survival in patients with advanced lung adenocarcinomas
Receptor, Epidermal Growth Factor
KRAS mutations predicted shorter survival for patients with advanced lung adenocarcinomas. The presence of EGFR and KRAS mutations define distinct subsets of patients with lung adenocarcinomas and should be determined in patients when they are diagnosed with advanced disease. Clinical trial reports should include EGFR and KRAS mutation status along with other prognostic factors.