Comparative effectiveness and cost-effectiveness of screening colonoscopy vs. Sigmoidoscopy and alternative strategies
Early Detection of Cancer
Health Care Costs
Quality-Adjusted Life Years
Screening colonoscopy may be cost-effective compared with FIT and sigmoidoscopy, depending on the relative rates of screening uptake and adherence and the protective benefit of colonoscopy in the proximal colon. Colonoscopy's cost-effectiveness compared with sigmoidoscopy is contingent on the ability to deliver ~50% protection against CRC in the proximal colon.