Phenotypic differences between pregnancy-onset and postpartum-onset major depressive disorder Academic Article uri icon

Overview

MeSH Major

  • Depression, Postpartum
  • Depressive Disorder, Major
  • Phenotype
  • Pregnancy Complications

abstract

  • Women with a history of perinatal and nonperinatal major depression are more likely to relapse during pregnancy than postpartum, a finding that points to the need for closely monitoring these women for depression during pregnancy. In addition, these findings of differences in risk factors and clinical features suggest that postpartum-onset major depression may have a pathophysiology distinct from major depression that begins during pregnancy. Time of onset of perinatal depression should be considered in the design of genetic and treatment studies.

publication date

  • December 2012

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.4088/JCP.12m07693

PubMed ID

  • 23290332

Additional Document Info

start page

  • e1485

end page

  • 91

volume

  • 73

number

  • 12