Designing a Type I Interferon Signaling Phagosome Comment uri icon

Overview

MeSH Major

  • Cystadenocarcinoma, Serous
  • Hypertension, Pulmonary
  • Lung Neoplasms
  • Neoplasms, Glandular and Epithelial
  • Neoplastic Cells, Circulating
  • Ovarian Neoplasms
  • Pulmonary Embolism
  • Thrombotic Microangiopathies

abstract

  • Circulating immune complexes trigger type I interferons exacerbating disease in systemic lupus erythematosus. In this issue of Immunity, Henault et al. (2012) show that Fcγ-receptor, Toll-like receptor 9, and LC3 conspire to mold phagosomes into type I interferon signaling platforms.

publication date

  • December 14, 2012

Research

keywords

  • Comment

Identity

Digital Object Identifier (DOI)

  • 10.1016/j.immuni.2012.11.009

PubMed ID

  • 23244713

Additional Document Info

start page

  • 947

end page

  • 9

volume

  • 37

number

  • 6