Carotid intimaemedia thickness: Ultrasound measurement, prognostic value and role in clinical practice Review uri icon


MeSH Major

  • Atherosclerosis
  • Carotid Intima-Media Thickness
  • Mass Screening


  • Ultrasound measurement of carotid intima-media thickness (IMT) has become a valuable tool for detecting and monitoring progression of atherosclerosis and recently published recommendations provide guidance for proper standardisation of these measurements. Important determinants of carotid IMT include age, gender, systolic blood pressure, diabetes mellitus and serum cholesterol levels. Many studies have shown carotid IMT to correlate with the severity of coronary atherosclerosis assessed by CT coronary calcification scores, coronary angiography and intravascular ultrasound. Consistent with its correlation with cardiovascular risk factors and coronary artery disease, a meta-analysis of large observational studies has shown carotid IMT to be a strong predictor of future cardiovascular events. Moreover, in patients with established coronary artery disease a reduction in carotid IMT has been shown to translate into a reduction in future cardiovascular events. Consensus statements now also recommend carotid IMT measurements to further refine the prognostic assessment of patients traditionally considered to be at an intermediate risk of cardiovascular disease.

publication date

  • December 2012



  • Review



  • eng

Digital Object Identifier (DOI)

  • 10.1136/postgradmedj-2011-130214

PubMed ID

  • 22761324

Additional Document Info

start page

  • 694

end page

  • 9


  • 88


  • 1046