Phase I trial of overlapping long peptides from a tumor self-antigen and poly-ICLC shows rapid induction of integrated immune response in ovarian cancer patients Academic Article uri icon

Overview

MeSH Major

  • Antigens, Neoplasm
  • Autoantigens
  • Cancer Vaccines
  • Carboxymethylcellulose Sodium
  • Ovarian Neoplasms
  • Peptides
  • Poly I-C
  • Polylysine

abstract

  • The current study shows that NY-ESO-1 OLP vaccine is safe and rapidly induces consistent integrated immune responses (antibody, CD8(+) and CD4(+)) in nearly all vaccinated patients when given with appropriate adjuvants.

publication date

  • December 2012

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1158/1078-0432.CCR-12-2189

PubMed ID

  • 23032745

Additional Document Info

start page

  • 6497

end page

  • 508

volume

  • 18

number

  • 23