Driver mutations determine survival in smokers and never-smokers with stage IIIB/IV lung adenocarcinomas
Receptor Protein-Tyrosine Kinases
Receptor, Epidermal Growth Factor
Never-smokers and former/current smokers with lung adenocarcinomas were not homogeneous subgroups. Each was made up of individuals whose tumors had a unique distribution of driver mutations, which were associated with different prognoses, irrespective of smoking history.