Comparative risk for angioedema associated with the use of drugs that target the renin-angiotensin-aldosterone system
Angiotensin Receptor Antagonists
Angiotensin-Converting Enzyme Inhibitors
Compared with β-blockers, ACEIs or aliskiren was associated with an approximately 3-fold higher risk for angioedema, although the number of exposed events for aliskiren was small. The risk for angioedema was lower with ARBs than with ACEIs or aliskiren.