Crypt base columnar stem cells in small intestines of mice are radioresistant Academic Article uri icon

Overview

MeSH Major

  • Adult Stem Cells
  • DNA Breaks, Double-Stranded
  • DNA Repair
  • Jejunum
  • Radiation Tolerance

abstract

  • Adult ISCs in mice can cycle rapidly yet still be radioresistant. Importantly, homologous recombination can protect adult stem cell populations from genotoxic stress. These findings broaden and refine concepts of the phenotype of adult stem cells.

publication date

  • November 2012

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3480544

Digital Object Identifier (DOI)

  • 10.1053/j.gastro.2012.07.106

PubMed ID

  • 22841781

Additional Document Info

start page

  • 1266

end page

  • 76

volume

  • 143

number

  • 5