Mismatch repair deficiency: A temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours Academic Article uri icon

Overview

MeSH Major

  • Adaptor Proteins, Signal Transducing
  • Antineoplastic Agents, Alkylating
  • Cerebellar Neoplasms
  • DNA Mismatch Repair
  • Dacarbazine
  • Drug Resistance, Neoplasm
  • Medulloblastoma
  • Nuclear Proteins

abstract

  • A subset of MB may respond to TMZ as some patient specimens are MGMT deficient, and tumours appear to be MMR proficient.

publication date

  • October 9, 2012

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3494444

Digital Object Identifier (DOI)

  • 10.1038/bjc.2012.403

PubMed ID

  • 22976800

Additional Document Info

start page

  • 1399

end page

  • 408

volume

  • 107

number

  • 8