A call for transparent reporting to optimize the predictive value of preclinical research. Academic Article uri icon

Overview

MeSH

  • Animals
  • Random Allocation
  • Sample Size
  • Statistics as Topic

MeSH Major

  • Publishing
  • Research Design

abstract

  • The US National Institute of Neurological Disorders and Stroke convened major stakeholders in June 2012 to discuss how to improve the methodological reporting of animal studies in grant applications and publications. The main workshop recommendation is that at a minimum studies should report on sample-size estimation, whether and how animals were randomized, whether investigators were blind to the treatment, and the handling of data. We recognize that achieving a meaningful improvement in the quality of reporting will require a concerted effort by investigators, reviewers, funding agencies and journal editors. Requiring better reporting of animal studies will raise awareness of the importance of rigorous study design to accelerate scientific progress.

authors

publication date

  • October 11, 2012

has subject area

  • Animals
  • Publishing
  • Random Allocation
  • Research Design
  • Sample Size
  • Statistics as Topic

Research

keywords

  • Journal Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3511845

Digital Object Identifier (DOI)

  • 10.1038/nature11556

PubMed ID

  • 23060188

Additional Document Info

start page

  • 187

end page

  • 191

volume

  • 490

number

  • 7419