The MeTeOR Trial (Meniscal Tear in Osteoarthritis Research): Rationale and design features Academic Article uri icon

Overview

MeSH Major

  • Arthroscopy
  • Knee Injuries
  • Menisci, Tibial

abstract

  • This paper presents the rationale and design features of the MeTeOR Trial (Meniscal Tear in Osteoarthritis Research; Clinical Trials.gov NCT00597012). MeTeOR is an NIH-funded seven-center prospective randomized controlled trial (RCT) designed to establish the efficacy of arthroscopic partial meniscectomy combined with a standardized physical therapy program as compared with a standardized physical therapy program alone in patients with a symptomatic meniscal tear in the setting of mild to moderate knee osteoarthritic change (OA). The design and execution of a trial that compares surgery with a nonoperative treatment strategy presents distinctive challenges. The goal of this paper is to provide the clinical rationale for MeTeOR and to highlight salient design features, with particular attention to those that present clinical and methodologic challenges.

publication date

  • November 2012

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3468667

Digital Object Identifier (DOI)

  • 10.1016/j.cct.2012.08.010

PubMed ID

  • 22968127

Additional Document Info

start page

  • 1189

end page

  • 96

volume

  • 33

number

  • 6