New insights into pancreatic cancer biology Article uri icon

Overview

MeSH Major

  • Carcinoma, Pancreatic Ductal
  • Pancreatic Neoplasms

abstract

  • Pancreatic cancer remains a devastating disease. Over the last few years, there have been important advances in the molecular and biological understanding of pancreatic cancer. This included understanding of the genomic complexity of the disease, the role of pancreatic cancer stem cells, the relevance of the tumor microenvironment, and the unique metabolic adaptation of pancreas cancer cells to obtain nutrients under hypoxic environment. In this paper, we review the most salient developments in these few areas.

publication date

  • September 2012

Research

keywords

  • Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1093/annonc/mds313

PubMed ID

  • 22987949

Additional Document Info

start page

  • x135

end page

  • 8

volume

  • 23

number

  • SUPPL. 10