Intensity modulated radiation therapy with dose painting to treat rhabdomyosarcoma
Academic Article
Overview
MeSH Major
Radiotherapy, Intensity-Modulated
Rhabdomyosarcoma
abstract
DP-IMRT with lower fractional and cumulative doses is feasible for very young children after second-look procedures with or without intraoperative RT. DP-IMRT is also feasible in adolescents and young adults with aggressive disease who would benefit from prophylactic RT to high-risk lymph node chains, although dose escalation might be warranted for improved local control. With limited follow-up, it appears that DP-IMRT produces local control rates comparable to those of sequential IMRT in patients with rhabdomyosarcoma.
