Diabetic neuropathy: Review of diagnosis and management
Diabetes Mellitus, Type 1
Diabetes Mellitus, Type 2
Diabetic neuropathy is common, under- or misdiagnosed, and causes not only substantial morbidity but also increased mortality. Apart from improving glycaemic control, there is no licensed treatment for diabetic neuropathy, although a number of pathogenetic pathways remain under active study. Focal and multifocal neuropathies are not common but can be extremely debilitating with few proven therapies. Autonomic dysfunction is more common, but si gnificant deficits, although severe, are relatively rare, with limited therapeutic options. Painful diabetic neuropathy is a cause of considerable morbidity and many pharmacological as well as non-pharmacological interventions have been used. The recent NICE (2010) guidance provides an evidence-based rationale for the management of neuropathic pain in primary care. © John Wiley and Sons 2008.
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