Bacterial genomics in infectious disease and the clinical pathology laboratory Review uri icon

Overview

MeSH Major

  • Bacterial Infections
  • Genome, Bacterial
  • Genomics

abstract

  • Many important discoveries bearing on infectious disease research and pathology laboratory practice have been achieved through whole-genome sequencing strategies. Bacterial genomics has improved our understanding of molecular pathogenesis, host-pathogen interactions, and antibiotic-resistance mechanisms. Bacterial genomics has also facilitated the study of population structures, epidemics and outbreaks, and newly identified pathogens. Many opportunities now exist for clinical pathologists to contribute to bacterial genomics, including in the design of new diagnostic tests, therapeutic agents, and vaccines.

publication date

  • November 2012

Research

keywords

  • Review

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.5858/arpa.2012-0025-RA

PubMed ID

  • 22439809

Additional Document Info

start page

  • 1414

end page

  • 22

volume

  • 136

number

  • 11