Imaging androgen receptor signaling with a radiotracer targeting free prostate-specific antigen Academic Article uri icon

Overview

MeSH Major

  • Molecular Imaging
  • Prostate-Specific Antigen
  • Radioactive Tracers
  • Receptors, Androgen
  • Signal Transduction

abstract

  • This report establishes that AR-dependent changes in PSA expression levels can be quantitatively measured at tumor lesions using a radiotracer that can be rapidly translated for human application and advances a new paradigm for radiotracer development that may more clearly highlight the unique virtues of an imaging biomarker.

publication date

  • April 2012

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3351274

Digital Object Identifier (DOI)

  • 10.1158/2159-8290.CD-11-0316

PubMed ID

  • 22576209

Additional Document Info

start page

  • 320

end page

  • 7

volume

  • 2

number

  • 4