Long-term outcomes after high-dose postprostatectomy salvage radiation treatment Academic Article uri icon

Overview

MeSH Major

  • Neoplasm Recurrence, Local
  • Prostatic Neoplasms
  • Salvage Therapy

abstract

  • Salvage RT provides effective long-term biochemical control and freedom from metastasis in selected patients presenting with detectable PSA after prostatectomy. Androgen-deprivation therapy was associated with improvement in biochemical progression-free survival. Clinical local failures were rare but occurred most commonly in patients with greater burden of disease at time of SRT as reflected by either radiographic imaging or a greater PSA level. Salvage radiation doses ≥70 Gy may ultimately be most beneficial in these patients, but this needs to be further studied.

publication date

  • September 2012

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.ijrobp.2011.10.077

PubMed ID

  • 22300563

Additional Document Info

start page

  • 112

end page

  • 8

volume

  • 84

number

  • 1