HLA-C-dependent prevention of leukemia relapse by donor activating KIR2DS1 Academic Article uri icon

Overview

MeSH Major

  • HLA-C Antigens
  • Leukemia, Myeloid, Acute
  • Receptors, KIR

abstract

  • Activating KIR genes from donors were associated with distinct outcomes of allogeneic HSCT for AML. Donor KIR2DS1 appeared to provide protection against relapse in an HLA-C-dependent manner, and donor KIR3DS1 was associated with reduced mortality. (Funded by the National Institutes of Health and others.).

publication date

  • August 30, 2012

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3767478

Digital Object Identifier (DOI)

  • 10.1056/NEJMoa1200503

PubMed ID

  • 22931314

Additional Document Info

start page

  • 805

end page

  • 16

volume

  • 367

number

  • 9