REM behavior disorder associated with familial amyotrophic lateral sclerosis. Academic Article uri icon

Overview

MeSH

  • Adult
  • Female
  • Humans
  • Male
  • Mutation

MeSH Major

  • Amyotrophic Lateral Sclerosis
  • REM Sleep Behavior Disorder
  • Superoxide Dismutase

abstract

  • The association between RBD and synucleinopathies is well known. However, the association between RBD and other neuromuscular diseases has not been as well described. Our case study describes two siblings with familial ALS, confirmed by the identification of the L84F mutation in the SOD1 gene, and RDB. We hope this case study will promote future studies on the prevalence of this association and will stimulate research in identifying the underlying pathogenic mechanism.

publication date

  • September 2012

has subject area

  • Adult
  • Amyotrophic Lateral Sclerosis
  • Female
  • Humans
  • Male
  • Mutation
  • REM Sleep Behavior Disorder
  • Superoxide Dismutase

Research

keywords

  • Case Reports
  • Journal Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.3109/17482968.2012.673172

PubMed ID

  • 22670878

Additional Document Info

start page

  • 473

end page

  • 474

volume

  • 13

number

  • 5