Efficacy of peripheral androgen blockade in prostate cancer patients with biochemical failure after definitive local therapy Academic Article uri icon

Overview

MeSH Major

  • 5-alpha Reductase Inhibitors
  • Adenocarcinoma
  • Androgen Antagonists
  • Antineoplastic Combined Chemotherapy Protocols
  • Prostatic Neoplasms

abstract

  • The use of the finasteride/flutamide combination is feasible, and results in PSA declines of ≥80% in 96% of patients with serologic progression after definitive local therapy. There were no unexpected toxicities, and the change in quality of life was mild. Further evaluation of this or a similar regimen in a controlled clinical trial is warranted.

publication date

  • September 2012

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC5558439

Digital Object Identifier (DOI)

  • 10.1002/cncr.26732

PubMed ID

  • 22180287

Additional Document Info

start page

  • 4139

end page

  • 47

volume

  • 118

number

  • 17