Decreased plasma cytokines are associated with low platelet counts in aplastic anemia and immune thrombocytopenic purpura Academic Article uri icon

Overview

MeSH Major

  • Anemia, Aplastic
  • Blood Platelets
  • Cytokines
  • Inflammation Mediators
  • Purpura, Thrombocytopenic, Idiopathic

abstract

  • Plasma CD40L, CXCL5, CCL5 and EGF are mainly platelet-derived, suggesting a role of platelets in immune responses and inflammation. Measurement of CD40L, CXCL5, CCL5 and EGF in human blood allowed testable inferences concerning physiology and pathophysiology in quantitative platelet disorders.

publication date

  • August 2012

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3419775

Digital Object Identifier (DOI)

  • 10.1111/j.1538-7836.2012.04757.x

PubMed ID

  • 22537155

Additional Document Info

start page

  • 1616

end page

  • 23

volume

  • 10

number

  • 8