Relationship of endothelial function and atherosclerosis to treatment response in late-life depression Academic Article uri icon

Overview

MeSH Major

  • Atherosclerosis
  • Depressive Disorder
  • Endothelium, Vascular

abstract

  • The results are consistent with a hypothesis that poorer antidepressant response in later life depressive disorder may be linked to an underlying vascular dysfunction and pathology. The study is small, and the results require replication but if confirmed, trials with vasoprotective medication aimed at improving vascular function in order to alter the prognosis of late-life depression would be a rational development.

publication date

  • September 2012

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1002/gps.2811

PubMed ID

  • 22228379

Additional Document Info

start page

  • 967

end page

  • 73

volume

  • 27

number

  • 9