Utility of glucose transporter 1 in the distinction of benign and malignant thoracic and abdominal mesothelial lesions Academic Article uri icon

Overview

MeSH Major

  • Abdominal Neoplasms
  • Glucose Transporter Type 1
  • Mesothelioma
  • Thoracic Neoplasms

abstract

  • Glucose transporter 1 staining of thoracic mesotheliomas showed high specificity but lower sensitivity than previously reported. Abdominal malignant mesotheliomas showed similar results. Because of low sensitivity, only positive staining is informative. In both sites, the utility of the stain was limited by nonspecific staining (eg, in necrotic areas) as well as bright labeling of erythrocytes and occasional lymphoid elements. Despite these limitations, GLUT-1 can help differentiate malignant mesothelioma from reactive benign mesothelium.

publication date

  • July 2012

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.5858/arpa.2011-0219-OA

PubMed ID

  • 22742553

Additional Document Info

start page

  • 804

end page

  • 9

volume

  • 136

number

  • 7