A replication study and genome-wide scan of single-nucleotide polymorphisms associated with pancreatic cancer risk and overall survival Academic Article uri icon

Overview

MeSH Major

  • ABO Blood-Group System
  • Genome-Wide Association Study
  • Pancreatic Neoplasms
  • Polymorphism, Single Nucleotide

abstract

  • The effects of SNPs on pancreatic cancer risk and OS were replicated in our study, although further work is necessary to understand the functional mechanisms underlying these effects. More importantly, the putative association with OS identified by GWAS suggests that GWAS may be useful in identifying SNPs associated with clinical outcome in pancreatic cancer.

publication date

  • July 15, 2012

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3568955

Digital Object Identifier (DOI)

  • 10.1158/1078-0432.CCR-11-2856

PubMed ID

  • 22665904

Additional Document Info

start page

  • 3942

end page

  • 51

volume

  • 18

number

  • 14