Atypical melanocytic proliferations and new primary melanomas in patients with advanced melanoma undergoing selective BRAF Inhibition Academic Article uri icon

Overview

MeSH Major

  • Melanoma
  • Protein Kinase Inhibitors
  • Proto-Oncogene Proteins B-raf
  • Skin Neoplasms

abstract

  • Malignant melanocytic tumors might develop with increased frequency in patients treated with selective BRAF inhibitors supporting a mechanism of BRAF therapy-induced growth and tumorigenesis. Careful surveillance of melanocytic lesions in patients receiving class I RAF inhibitors seems warranted.

publication date

  • July 2012

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3646308

Digital Object Identifier (DOI)

  • 10.1200/JCO.2011.41.1660

PubMed ID

  • 22614973

Additional Document Info

start page

  • 2375

end page

  • 83

volume

  • 30

number

  • 19