Dendritic cells with TGF-β1 and IL-2 differentiate naive CD4+ T Cells into alloantigen-specific and allograft protective foxp3+ regulatory T cells Academic Article uri icon

Overview

MeSH Major

  • CD4-Positive T-Lymphocytes
  • Cell Differentiation
  • Dendritic Cells
  • Forkhead Transcription Factors
  • Interleukin-2
  • T-Lymphocytes, Regulatory
  • Transforming Growth Factor beta1

abstract

  • A combination of CD11c+ DCs, IL-2, and TGF-β1 may help differentiate naive, high abundant CD4+ T into alloantigen-specific and allograft protective Foxp3+Tregs.

publication date

  • March 27, 2012

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3595618

Digital Object Identifier (DOI)

  • 10.1097/TP.0b013e318244dd67

PubMed ID

  • 22270834

Additional Document Info

start page

  • 580

end page

  • 8

volume

  • 93

number

  • 6