Longitudinal computational fluid dynamics study of aneurysmal dilatation in a chronic DeBakey type III aortic dissection Academic Article uri icon

Overview

MeSH Major

  • Aneurysm, Dissecting
  • Aortic Aneurysm
  • Hydrodynamics

abstract

  • Computational fluid dynamics, which uses numeric methods and algorithms for the simulation of blood flow by solving the Navier-Stokes equations on computational meshes, is enhancing the understanding of disease progression in type III aortic dissections. To illustrate this, we examined the changes in patient-derived geometries of aortic dissections, which showed progressive false lumen aneurysmal dilatation (26% diameter increase) during follow-up. Total pressure was decreased by 29% during systole and by 34% during retrograde flow. At the site of the highest false lumen dilatation, the temporal average of total pressure decreased from 45 to 22 Pa, and maximal average wall shear stress decreased from 0.9 to 0.4 Pa. These first results in the study of disease progression of type III DeBakey aortic dissection with computational fluid dynamics are encouraging.

publication date

  • July 2012

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.jvs.2012.02.064

PubMed ID

  • 22579075

Additional Document Info

start page

  • 260

end page

  • 3.e1

volume

  • 56

number

  • 1