Microscopically positive margins for primary gastrointestinal stromal tumors: Analysis of risk factors and tumor recurrence
Gastrointestinal Stromal Tumors
Neoplasm Recurrence, Local
Approximately 9% of 819 GIST patients had an R1 resection. Significant factors associated with R1 resection include tumor size ≥ 10 cm, location, and rupture. The difference in recurrence-free survival with or without imatinib therapy in those undergoing an R1 vs R0 resection was not statistically significant at a median follow-up of 4 years.