Acute myeloid leukemia and myelodysplastic syndromes after radiation therapy are similar to de novo disease and differ from other therapy-related myeloid neoplasms Academic Article uri icon

Overview

MeSH Major

  • Leukemia, Myeloid, Acute
  • Myelodysplastic Syndromes
  • Neoplasms, Radiation-Induced
  • Neoplasms, Second Primary

abstract

  • AML and MDS diagnosed in the past decade in patients after receiving XRT alone differ from t-MN occurring after C/CMT and share genetic features and clinical behavior with de novo AML/MDS. Our results suggest that post-XRT MDS/AML may not represent a direct consequence of radiation toxicity and warrant a therapeutic approach similar to de novo disease.

publication date

  • July 2012

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4979234

Digital Object Identifier (DOI)

  • 10.1200/JCO.2011.38.7340

PubMed ID

  • 22585703

Additional Document Info

start page

  • 2340

end page

  • 7

volume

  • 30

number

  • 19