Variation of second cancer risk by family history of retinoblastoma among long-term survivors Academic Article uri icon

Overview

MeSH Major

  • Genetic Predisposition to Disease
  • Germ-Line Mutation
  • Neoplasms, Second Primary
  • Retinal Neoplasms
  • Retinoblastoma
  • Retinoblastoma Protein
  • Survivors

abstract

  • Rb survivors with bilateral disease and an inherited germline mutation are at slightly higher risk of an SC compared with those with a de novo germline mutation, in particular melanoma, perhaps because of shared genetic alterations.

publication date

  • March 20, 2012

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3341108

Digital Object Identifier (DOI)

  • 10.1200/JCO.2011.37.0239

PubMed ID

  • 22355046

Additional Document Info

start page

  • 950

end page

  • 7

volume

  • 30

number

  • 9