Intraneuronal Aβ accumulation, amyloid plaques, and synapse pathology in Alzheimer's disease Academic Article uri icon

Overview

MeSH Major

  • Alzheimer Disease
  • Neurofibrillary Tangles
  • Neurons
  • Plaque, Amyloid
  • Synapses

abstract

  • The data support that Aβ42 accumulation and aggregation begin within AD-vulnerable neurons in the brain. Progressive intraneuronal Aβ42 aggregation disrupts the normal cytoarchitecture of neurites.

publication date

  • April 2012

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1159/000334762

PubMed ID

  • 22269167

Additional Document Info

start page

  • 56

end page

  • 9

volume

  • 10

number

  • 1-4