Expanding the spectrum of monoclonal light chain deposition disease in muscle Academic Article uri icon

Overview

MeSH Major

  • Immunoglobulin Light Chains
  • Muscle, Skeletal
  • Paraproteinemias

abstract

  • The spectrum of immunoglobulin deposition in muscle is similar to other organs. It comprises a continuum that includes parenchymal amyloid deposition, amyloid angiopathy, and noncongophilic Light Chain Deposition Disease (LCDD). We recommend including the FLC assay in the routine investigation for monoclonal gammopathies. This case also highlights the value of MRI-guided muscle biopsy.

publication date

  • May 2012

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4133774

Digital Object Identifier (DOI)

  • 10.1002/mus.23287

PubMed ID

  • 22499107

Additional Document Info

start page

  • 755

end page

  • 61

volume

  • 45

number

  • 5