Intra-arterial chemotherapy for retinoblastoma in eyes with vitreous and/or subretinal seeding: 2-Year results Academic Article uri icon

Overview

MeSH Major

  • Antineoplastic Agents
  • Choroid Neoplasms
  • Neoplasm Seeding
  • Retinal Neoplasms
  • Retinoblastoma
  • Vitreous Body

abstract

  • Unlike radiation or systemic chemotherapy, intra-arterial chemotherapy can usually prevent the need for enucleation in naive eyes with advanced intraocular retinoblastoma with seeding-especially if the seeding is subretinal. Treatment appears to be less effective in previously treated eyes when subretinal seeding is present (50% at 2 years), but may be more effective in eyes that failed to respond to previous systemic chemotherapy and have only vitreous seeding.

publication date

  • April 2012

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1136/bjophthalmol-2011-300498

PubMed ID

  • 22053101

Additional Document Info

start page

  • 499

end page

  • 502

volume

  • 96

number

  • 4