Meta-analysis of genome-wide linkage scans for renal function traits Review uri icon

Overview

MeSH Major

  • Genetic Linkage
  • Genetic Predisposition to Disease
  • Genome-Wide Association Study
  • Kidney Failure, Chronic

abstract

  • While heterogeneity across populations, methodologies and study designs likely explain this lack of agreement, it is possible that linkage scan methodologies lack the resolution for investigating complex traits. Combining family-based linkage studies with genome-wide association studies may be a powerful approach to detect private mutations contributing to complex renal phenotypes.

publication date

  • February 2012

Research

keywords

  • Review

Identity

Language

  • eng

PubMed Central ID

  • PMC3275782

Digital Object Identifier (DOI)

  • 10.1093/ndt/gfr255

PubMed ID

  • 21622988

Additional Document Info

start page

  • 647

end page

  • 56

volume

  • 27

number

  • 2