Melanoma of the lentigo maligna subtype: Diagnostic challenges and current treatment paradigms Review uri icon

Overview

MeSH Major

  • Hutchinson's Melanotic Freckle
  • Skin Neoplasms

abstract

  • Melanoma of the lentigo maligna subtype presents diagnostic and treatment challenges because of ill-defined clinical margins in cosmetically and functionally sensitive areas of the head and neck with extensive sun damage. This review highlights the natural history, varied clinical presentations, and pitfalls in histologic diagnosis. The focus is on the surgical management, comparing excision and pathologic tissue processing techniques of wide excision, Mohs micrographic surgery, and staged excision. Staged excision is recommended for optimal surgical margin control. Nonsurgical treatment modalities are also reviewed for the elderly or unresectable cases.

publication date

  • February 2012

Research

keywords

  • Review

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1097/PRS.0b013e31823aeb72

PubMed ID

  • 22286443

Additional Document Info

start page

  • 288e

end page

  • 299e

volume

  • 129

number

  • 2