Napsin A, a new marker for lung adenocarcinoma, is complementary and more sensitive and specific than thyroid transcription factor 1 in the differential diagnosis of primary pulmonary carcinoma: Evaluation of 1674 cases by tissue microarray Academic Article uri icon

Overview

MeSH Major

  • Adenocarcinoma
  • Aspartic Acid Endopeptidases
  • Carcinoma, Non-Small-Cell Lung
  • Carcinoma, Small Cell
  • Lung Neoplasms
  • Nuclear Proteins
  • Transcription Factors

abstract

  • Nap-A is superior to TTF-1 in distinguishing primary lung ACA from other carcinomas (except kidney), particularly primary lung small cell carcinoma, and primary thyroid carcinoma. A combination of Nap-A and TTF-1 is useful in the distinction of primary lung ACA (Nap-A(+), TTF-1(+)) from primary lung squamous cell carcinoma (Nap-A(-), TTF-1(-)) and primary lung small cell carcinoma (Nap-A(-), TTF-1(+)).

publication date

  • February 2012

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.5858/arpa.2011-0320-OA

PubMed ID

  • 22288963

Additional Document Info

start page

  • 163

end page

  • 71

volume

  • 136

number

  • 2