Autophagy: cellular defense to excessive inflammation. Review uri icon

Overview

MeSH

  • Animals
  • Humans
  • Signal Transduction

MeSH Major

  • Autophagy
  • Immunity, Cellular
  • Inflammation

abstract

  • Autophagy can orchestrate a variety of cellular responses to dangerous stimuli. Our understanding of the physiologic roles of autophagy has recently expanded; in addition to its other roles, autophagy now appears to play an essential role in regulating inflammatory responses. This review describes recent findings concerning the roles and mechanisms of autophagy in controlling excessive inflammation. Copyright © 2011 Institut Pasteur. All rights reserved.

publication date

  • February 2012

has subject area

  • Animals
  • Autophagy
  • Humans
  • Immunity, Cellular
  • Inflammation
  • Signal Transduction

Research

keywords

  • Journal Article
  • Review

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.micinf.2011.08.014

PubMed ID

  • 21924374

Additional Document Info

start page

  • 119

end page

  • 125

volume

  • 14

number

  • 2