Prevalence of BRCA1 and BRCA2 mutations in Ashkenazi Jewish families with breast and pancreatic cancer Academic Article uri icon

Overview

MeSH Major

  • Breast Neoplasms
  • Genes, BRCA1
  • Genes, BRCA2
  • Germ-Line Mutation
  • Jews
  • Pancreatic Neoplasms

abstract

  • BRCA1 and BRCA2 mutations are observed with nearly equal distribution in AJ breast-pancreas cancer families, suggesting that both genes are associated with PC risk. In this population, a FH of PC was found to have a limited effect on mutation prevalence.

publication date

  • January 15, 2012

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1002/cncr.26191

PubMed ID

  • 21598239

Additional Document Info

start page

  • 493

end page

  • 9

volume

  • 118

number

  • 2