Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer Academic Article uri icon

Overview

MeSH Major

  • Antineoplastic Combined Chemotherapy Protocols
  • Carcinoma, Non-Small-Cell Lung
  • Lung Neoplasms

abstract

  • This study demonstrates that combined epigenetic therapy with low-dose azacitidine and entinostat results in objective, durable responses in patients with solid tumors and defines a blood-based biomarker that correlates with clinical benefit.

publication date

  • December 2011

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3353724

Digital Object Identifier (DOI)

  • 10.1158/2159-8290.CD-11-0214

PubMed ID

  • 22586682

Additional Document Info

start page

  • 598

end page

  • 607

volume

  • 1

number

  • 7