Challenging the feasibility and clinical significance of current guidelines on lymph node examination in rectal cancer in the era of neoadjuvant therapy Academic Article uri icon

Overview

MeSH Major

  • Lymph Nodes
  • Neoadjuvant Therapy
  • Neoplasm Staging
  • Practice Guidelines as Topic
  • Rectal Neoplasms

abstract

  • In a tertiary cancer center, the 12-LN threshold was not relevant and often not achievable in patients with RC treated with neoadjuvant therapy. Lower LN count after neoadjuvant treatment was not associated with understaging or inferior survival. Although we support the critical importance of careful pathologic examination and adequate nodal staging, we challenge the relevance of LN count both in clinical practice and as a quality indicator in RC.

publication date

  • December 2011

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3646313

Digital Object Identifier (DOI)

  • 10.1200/JCO.2011.37.2235

PubMed ID

  • 21990400

Additional Document Info

start page

  • 4568

end page

  • 73

volume

  • 29

number

  • 34