Human epidermal growth factor receptor 2 testing in gastroesophageal cancer: Correlation between immunohistochemistry and fluorescence in situ hybridization Academic Article uri icon

Overview

MeSH Major

  • Esophageal Neoplasms
  • Esophagogastric Junction
  • Receptor, ErbB-2
  • Stomach Neoplasms

abstract

  • Human epidermal growth factor receptor 2 testing in gastroesophageal cancer can be performed using standard breast cancer procedures and the American Society of Clinical Oncology/College of American Pathologists scoring criteria. Although IHC 0 and IHC 3+ provide clear stratification, reliable separation of IHC 1+ and IHC 2+ may be difficult, especially in biopsy samples. The latter 2 groups are best referred to FISH for definitive classification.

publication date

  • November 2011

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.5858/arpa.2010-0541-OA

PubMed ID

  • 22032573

Additional Document Info

start page

  • 1460

end page

  • 5

volume

  • 135

number

  • 11