Circulating markers of vascular injury and angiogenesis in antineutrophil cytoplasmic antibody-associated vasculitis Academic Article uri icon

Overview

MeSH Major

  • Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
  • E-Selectin
  • Matrix Metalloproteinase 3
  • Neovascularization, Pathologic
  • Vascular System Injuries

abstract

  • Many markers of vascular injury and angiogenesis are elevated in severe active AAV and decline with treatment, but MMP-3 appears to distinguish active AAV from remission better than the other markers studied. Further study of MMP-3 is warranted to determine its clinical utility in combination with conventional markers of inflammation and ANCA titers.

publication date

  • December 2011

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3227746

Digital Object Identifier (DOI)

  • 10.1002/art.30615

PubMed ID

  • 21953143

Additional Document Info

start page

  • 3988

end page

  • 97

volume

  • 63

number

  • 12