Gut microbiota and the role of probiotics in therapy Review uri icon

Overview

MeSH Major

  • Intestinal Diseases
  • Intestines
  • Metagenome
  • Probiotics

abstract

  • Thanks to rapid progress in the development and application of molecular techniques to the assessment of the human gut microbiome, the true nature, diversity and metabolic potential of this 'hidden organ' are being revealed. Simultaneously, the complex physiological, immunological and metabolic interactions between host and microbiome are being untangled. By contrast, the probiotic concept has been with us for decades and, while supported more by fad and folklore in the past, is now gaining support, not only from experimental work in animal models, but also by well-designed studies in human diseases, most notably infectious diarrheas, inflammatory bowel disease and the irritable bowel syndrome.

publication date

  • December 2011

Research

keywords

  • Review

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.coph.2011.09.010

PubMed ID

  • 21996283

Additional Document Info

start page

  • 593

end page

  • 603

volume

  • 11

number

  • 6