Differences in platelet function in patients with acute myeloid leukemia and myelodysplasia compared to equally thrombocytopenic patients with immune thrombocytopenia Academic Article uri icon

Overview

MeSH Major

  • Blood Platelets
  • Leukemia, Myeloid, Acute
  • Myelodysplastic Syndromes
  • Purpura, Thrombocytopenic, Idiopathic

abstract

  • AML/MDS patients have lower in vivo platelet activation and ex vivo platelet reactivity than patients with ITP. The proportion of newly produced platelets correlates with the expression of platelet surface markers of activation. These differences might contribute to differences in bleeding tendency between AML/MDS and ITP patients. This study is the first to define differences in platelet function between AML/MDS patients and ITP patients with equivalent degrees of thrombocytopenia.

publication date

  • November 2011

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3210015

Digital Object Identifier (DOI)

  • 10.1111/j.1538-7836.2011.04506.x

PubMed ID

  • 21920014

Additional Document Info

start page

  • 2302

end page

  • 10

volume

  • 9

number

  • 11