Anti-Müllerian hormone reduces follicle sensitivity to follicle-stimulating hormone in human granulosa cells Academic Article uri icon

Overview

MeSH Major

  • Anti-Mullerian Hormone
  • Follicle Stimulating Hormone
  • Granulosa Cells
  • Ovarian Follicle

abstract

  • The AMH inhibits factors affecting FSH sensitivity. As AMH levels decrease with follicle growth, this inhibition would be removed. The AMH overproduction in anovulatory polycystic ovaries (PCO) may therefore restrict folliculogenesis by an inhibitory effect on FSH sensitivity, thereby contributing to anovulation.

publication date

  • November 2011

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.fertnstert.2011.08.015

PubMed ID

  • 21917251

Additional Document Info

start page

  • 1246

end page

  • 51.e1

volume

  • 96

number

  • 5