Fetal and neonatal alloimmune thrombocytopenia: A management algorithm based on risk stratification Academic Article uri icon

Overview

MeSH Major

  • Algorithms
  • Thrombocytopenia, Neonatal Alloimmune

abstract

  • Fetal and neonatal alloimmune thrombocytopenia constitutes the most common cause of severe thrombocytopenia in fetuses and neonates and of intracranial hemorrhage among term newborns. The cornerstone of therapy involves the use of steroids and intravenous immunoglobulins. Despite the risk of potentially devastating consequences to the fetus, fetal blood sampling has typically been used to document response to therapy. We propose a therapeutic algorithm based on risk stratification with individualized treatment optimization without the use of fetal blood sampling.

publication date

  • November 2011

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1097/AOG.0b013e31823403f4

PubMed ID

  • 22015886

Additional Document Info

start page

  • 1157

end page

  • 63

volume

  • 118

number

  • 5