Noninvasive cardiac output monitoring with bioreactance as an alternative to invasive instrumentation for preclinical drug evaluation in beagles Academic Article uri icon

Overview

MeSH Major

  • Aorta
  • Cardiac Output
  • Monitoring, Physiologic
  • Neuromuscular Blocking Agents

abstract

  • Continuous, non-invasive measurement of CO by bioreactance provides data that satisfactorily approximates invasive measurement of aortic blood flow in beagles. In addition, despite a 30s interval between measurements, the NICOM appears to have sufficient fidelity to detect and quantify acute, drug-induced changes in CO. These data suggest that the NICOM may represent an alternative to open chest instrumentation for CO measurement in preclinical drug evaluation studies.

publication date

  • September 2011

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.vascn.2011.03.006

PubMed ID

  • 21440649

Additional Document Info

start page

  • 111

end page

  • 8

volume

  • 64

number

  • 2