Anti-nuclear antibody positivity and the use of certolizumab in inflammatory bowel disease patients who have had arthralgias or lupus-like reactions from infliximab or adalimumab Academic Article uri icon

Overview

MeSH Major

  • Antibodies, Antinuclear
  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Humanized
  • Arthralgia
  • Immunoglobulin Fab Fragments
  • Inflammatory Bowel Diseases
  • Lupus Erythematosus, Systemic
  • Polyethylene Glycols
  • Tumor Necrosis Factor-alpha

abstract

  • Nearly all patients experienced relief from their lupus-like symptoms with certolizumab and 2 out of 4 patients reversed their ANA positivity. While future investigation is warranted, patients who have lupus-like reactions from infliximab or adalimumab may benefit from switching to certolizumab.

publication date

  • October 2011

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1111/j.1751-2980.2011.00522.x

PubMed ID

  • 21955431

Additional Document Info

start page

  • 379

end page

  • 83

volume

  • 12

number

  • 5